2799607-58-0
2799607-58-0
Chemical Structure
MtTMPK-IN-1
- CAS No.: 2799607-58-0
- Formula:C22H24N4O3
- Molecular Weight:392.45
IUPAC Name: 5-methyl-1-(1-((6-phenoxypyridin-2-yl)methyl)piperidin-4-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: BKRRWLAIGUKKJX-UHFFFAOYSA-N
SMILES: CC1=CN(C(NC1=O)=O)C2CCN(CC2)CC3=NC(OC4=CC=CC=C4)=CC=C3
Biological Activity: MtTMPK-IN-1 (compound 3) is a potent Mycobacterium tuberculosis thymidylate kinase (MtTMPK) inhibitor with an IC50 value of 2.5 μM. MtTMPK-IN-1 has moderate to weak activity against Mtb H37Rv and low cytotoxicity in human fibroblast cells MRC-5. MtTMPK-IN-1 can be used for researching tuberculosis[1].
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MtTMPK-IN-1 | MtTMPK-IN-1 (compound 3) is a potent Mycobacterium tuberculosis thymidylate kinase (MtTMPK) inhibitor with an IC50 value of 2.5 μM. MtTMPK-IN-1 has moderate to weak activity against Mtb H37Rv and low cytotoxicity in human fibroblast cells MRC-5. MtTMPK-IN-1 can be used for researching tuberculosis. | |||||||||||||||||||||
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