2813268-66-3
2813268-66-3
Chemical Structure
(5-Cl)-Exatecan
- CAS No.: 2813268-66-3
- Formula:C24H22ClN3O4
- Molecular Weight:451.90
InChIKey: RNPTYUSCHGJZAQ-FYSMJZIKSA-N
SMILES: N[C@@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(Cl)=C(C)C(CC1)=C62
Biological Activity: (5-Cl)-Exatecan is a derivative of Exatecan (HY-13631) and a DNA topoisomerase inhibitor. (5-Cl)-Exatecan serves as the cytotoxic payload component in antibody-drug conjugates (ADC) targeting ROR1-positive cancers. (5-Cl)-Exatecan is applicable for the research of ROR1-positive cancers[1].
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(5-Cl)-Exatecan | (5-Cl)-Exatecan is a derivative of Exatecan (HY-13631) and a DNA topoisomerase inhibitor. (5-Cl)-Exatecan serves as the cytotoxic payload component in antibody-drug conjugates (ADC) targeting ROR1-positive cancers. (5-Cl)-Exatecan is applicable for the research of ROR1-positive cancers. | |||||||||||||||||||||
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References
Keywords
