2825567-86-8
2825567-86-8
Chemical Structure
Cathepsin C-IN-4
- CAS No.: 2825567-86-8
- Formula:C21H14ClF3N4S
- Molecular Weight:446.88
IUPAC Name: 5-chloro-N2-(3-(thiophen-3-yl)phenyl)-N4-(3-(trifluoromethyl)phenyl)pyrimidine-2,4-diamine
InChIKey: OSDVAFDKKPSJHP-UHFFFAOYSA-N
SMILES: FC(F)(C1=CC=CC(NC2=C(C=NC(NC3=CC=CC(C4=CSC=C4)=C3)=N2)Cl)=C1)F
Biological Activity: Cathepsin C-IN-4 (compound SF27) is a potent Cathepsin C (Cat C) inhibitor, with an IC50 of 65.6 nM. Cathepsin C-IN-4 also inhibits THP-1 and U937 cell, with IC50 values of 203.4 and 177.6 nM, respectively[1].
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Cathepsin C-IN-4 | Cathepsin C-IN-4 (compound SF27) is a potent Cathepsin C (Cat C) inhibitor, with an IC50 of 65.6 nM. Cathepsin C-IN-4 also inhibits THP-1 and U937 cell, with IC50 values of 203.4 and 177.6 nM, respectively. | |||||||||||||||||||||
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References
Keywords
