2832824-40-3
Chemical Structure
EB-0150
- CAS No.: 2832824-40-3
- Formula:C19H30N6O7
- Molecular Weight:454.48
IUPAC Name: (1S,2S,3R,4S,5S)-5-((6-((4-azido-2-nitrophenyl)amino)hexyl)amino)-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetraol
InChIKey: LQGVNQLERZVIBK-UJCHZGTJSA-N
SMILES: O[C@@H]1[C@](O)(C[C@@H]([C@@H]([C@H]1O)O)NCCCCCCNC2=C(C=C(C=C2)N=[N+]=[N-])[N+]([O-])=O)CO
Biological Activity: EB-0150 is a potent inhibitor of ER α-glucosidases (α-Glu) Iand II with IC50s of 0.73 and 0.0337 μM, respectively. EB-0150 is a N-substituted derivative of valiolamine with broad-spectrum antiviral. EB-0150 has the potential for the reseach of broad-spectrum agent against the existing and emerging viruses[1]. EB-0150 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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EB-0150 | EB-0150 is a potent inhibitor of ER α-glucosidases (α-Glu) Iand II with IC50s of 0.73 and 0.0337 μM, respectively. EB-0150 is a N-substituted derivative of valiolamine with broad-spectrum antiviral. EB-0150 has the potential for the reseach of broad-spectrum agent against the existing and emerging viruses. EB-0150 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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