28434-00-6
Chemical Structure
S-Bioallethrin
Synonym(s): D-Trans-Allethrin; Esbiol
- CAS No.: 28434-00-6
- Formula:C19H26O3
- Molecular Weight:302.41
IUPAC Name: (S)-3-allyl-2-methyl-4-oxocyclopent-2-en-1-yl (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxylate
InChIKey: ZCVAOQKBXKSDMS-PVAVHDDUSA-N
SMILES: C/C(C)=C\[C@@H]1[C@H](C1(C)C)C(O[C@@H]2C(C)=C(C(C2)=O)CC=C)=O
Biological Activity: S-Bioallethrin (D-Trans-Allethrin) is a pyrethroid insecticide. S-Bioallethrin disrupts nerve function by modifying the gating kinetics of transitions between the conducting and nonconducting states of voltage-gated sodium channels. S-Bioallethrin also causes inhibition of lymphocyte proliferation and induces histamine release from human basophils[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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S-Bioallethrin | 98.16% | S-Bioallethrin (D-Trans-Allethrin) is a pyrethroid insecticide. S-Bioallethrin disrupts nerve function by modifying the gating kinetics of transitions between the conducting and nonconducting states of voltage-gated sodium channels. S-Bioallethrin also causes inhibition of lymphocyte proliferation and induces histamine release from human basophils. | ||||||||||||||||||||
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- [1]. McCavera SJ, et al. Differential state-dependent modification of inactivation-deficient Nav1.6 sodium channels by the pyrethroid insecticides S-bioallethrin, tefluthrin and deltamethrin. Neurotoxicology. 2012;33(3):384-390. [Content Brief]
- [2]. Diel F, et al. In vitro effects of the pyrethroid S-bioallethrin on lymphocytes and basophils from atopic and nonatopic subjects. Allergy. 1998 Nov;53(11):1052-9. [Content Brief]
- [3]. Tan J, et al. Divergent actions of the pyrethroid insecticides S-bioallethrin, tefluthrin, and deltamethrin on rat Na(v)1.6 sodium channels. Toxicol Appl Pharmacol. 2010 Sep 15;247(3):229-37. [Content Brief]
- [4]. Ray DE, Burr SA, Lister T. The effects of combined exposure to the pyrethroids deltamethrin and S-bioallethrin on hippocampal inhibition and skeletal muscle hyperexcitability in rats. Toxicol Appl Pharmacol. 2006 Oct 15;216(2):354-62. [Content Brief]
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