2863-04-9
Chemical Structure
Thymidine 3',5'-disphosphate
Synonym(s): Deoxythymidine 3′,5′-diphosphate; pdTp
- CAS No.: 2863-04-9
- Formula:C10H16N2O11P2
- Molecular Weight:402.19
IUPAC Name: ((2R,3S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-(phosphonooxy)tetrahydrofuran-2-yl)methyl dihydrogen phosphate
InChIKey: CSNCBOPUCJOHLS-XLPZGREQSA-N
SMILES: OP(O)(O[C@H]1C[C@H](N2C(NC(C(C)=C2)=O)=O)O[C@@H]1COP(O)(O)=O)=O
Biological Activity: Thymidine 3',5'-disphosphate (Deoxythymidine 3′,5′-diphosphate; pdTp) is a selective small molecule inhibitor of staphylococcal nuclease and tudor domain containing 1 (SND1, the miRNA regulatory complex RISC subunit) and inhibits SND1 activity. Thymidine 3',5'-disphosphate exhibits anti-tumor efficacy in vivo[1].
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Thymidine 3',5'-disphosphate | Thymidine 3',5'-disphosphate (Deoxythymidine 3′,5′-diphosphate; pdTp) is a selective small molecule inhibitor of staphylococcal nuclease and tudor domain containing 1 (SND1, the miRNA regulatory complex RISC subunit) and inhibits SND1 activity. Thymidine 3',5'-disphosphate exhibits anti-tumor efficacy in vivo. | |||||||||||||||||||||
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Keywords
