2870703-21-0
Chemical Structure
Antitumor agent-77
- CAS No.: 2870703-21-0
- Formula:C7H11F3N2O5Pt
- Molecular Weight:455.25
InChIKey: UYMYSVQQMXLTHF-UHFFFAOYSA-L
SMILES: O=C1[O-][Pt+2]([NH3])([NH3])[O-]C(C12CC(C2)(C(F)(F)F)O)=O
Biological Activity: Antitumor agent-77 is an antitumor agent, inhibits cancer cells growth and migration. Antitumor agent-77 triggers ferroptosis by inhibiting GPx-4 and elevating COX2. Antitumor agent-77 also activates intrinsic apoptotic pathway (Bax-Bcl-2-caspase-3) and hinders Epithelial-mesenchymal transition (EMT) process of cancer cells[1].
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Antitumor agent-77 | Antitumor agent-77 is an antitumor agent, inhibits cancer cells growth and migration. Antitumor agent-77 triggers ferroptosis by inhibiting GPx-4 and elevating COX2. Antitumor agent-77 also activates intrinsic apoptotic pathway (Bax-Bcl-2-caspase-3) and hinders Epithelial-mesenchymal transition (EMT) process of cancer cells. | |||||||||||||||||||||
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Keywords