288077-60-1
288077-60-1
Chemical Structure
BMS-269223
- CAS No.: 288077-60-1
- Formula:C23H28N6O3
- Molecular Weight:436.51
IUPAC Name: (S,E)-2-cyano-1-(2-methylbenzofuran-5-yl)-3-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)azepan-3-yl)guanidine
InChIKey: BQUXAJWDRCSKFN-IBGZPJMESA-N
SMILES: CC(O1)=CC2=C1C=CC(N/C(N[C@H]3CCCCN(CC(N4CCCC4)=O)C3=O)=N/C#N)=C2
Biological Activity: BMS-269223 is a potent, selective and orally active factor Xa inhibitor (Ki = 6.5 nM, EC2xPT = 32 μM). BMS-269223 can prolong prothrombin time and inhibit thrombosis formation. BMS-269223 can be used for the research of cardiovascular disease[1].
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BMS-269223 | BMS-269223 is a potent, selective and orally active factor Xa inhibitor (Ki = 6.5 nM, EC2xPT = 32 μM). BMS-269223 can prolong prothrombin time and inhibit thrombosis formation. BMS-269223 can be used for the research of cardiovascular disease. | |||||||||||||||||||||
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References
Keywords
