288144-20-7
288144-20-7
Chemical Structure
VEGFR-2-IN-44
- CAS No.: 288144-20-7
- Formula:C17H15BrN2O
- Molecular Weight:343.22
IUPAC Name: (Z)-5-bromo-3-((4,5,6,7-tetrahydro-1H-indol-2-yl)methylene)indolin-2-one
InChIKey: RFHPWPWVGFSLOP-ZROIWOOFSA-N
SMILES: O=C(/C(C1=C2)=C\C3=CC4=C(CCCC4)N3)NC1=CC=C2Br
Biological Activity: VEGFR-2-IN-44 (compound 4b) is a selective VEGF-R2 (Flk-1) inhibitor with an IC50 value of 70 nM. VEGFR-2-IN-44 also inhibits PDGF-Rβ with an IC50 of 920 nM[1].
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VEGFR-2-IN-44 | VEGFR-2-IN-44 (compound 4b) is a selective VEGF-R2 (Flk-1) inhibitor with an IC50 value of 70 nM. VEGFR-2-IN-44 also inhibits PDGF-Rβ with an IC50 of 920 nM. | |||||||||||||||||||||
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References
Keywords
