2890621-88-0
2890621-88-0
Chemical Structure
EGFR-IN-126
- CAS No.: 2890621-88-0
- Formula:C28H28BrFN4O3
- Molecular Weight:567.45
InChIKey: GLGATRQBEFEOKX-UHFFFAOYSA-N
SMILES: COC1=C(OCC2CCN(C)CC2)C=C(N=CN=C3NC4=CC=C(OC5=CC=CC=C5F)C(Br)=C4)C3=C1
Biological Activity: EGFR-IN-126 (compound 9d) is a potent inhibitor of EGFRL858R/T790M/C797S, with the IC50 value of 0.005 μM. EGFR-IN-126 shows antitumor effects in vivo and in vitro[1].
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EGFR-IN-126 | EGFR-IN-126 (compound 9d) is a potent inhibitor of EGFRL858R/T790M/C797S, with the IC50 value of 0.005 μM. EGFR-IN-126 shows antitumor effects in vivo and in vitro. | |||||||||||||||||||||
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References
Keywords
