2902563-76-0
2902563-76-0
Chemical Structure
Anticancer agent 36
- No. CAS: 2902563-76-0
- Formula:C21H17N3O3S2
- Molecular Weight:423.51
IUPAC Name: 4-methyl-N-((4-(naphthalen-2-yl)thiazol-2-yl)carbamoyl)benzenesulfonamide
InChIKey: LOPHKIBWIYDHOP-UHFFFAOYSA-N
SMILES: CC1=CC=C(C=C1)S(=O)(NC(NC2=NC(C3=CC4=C(C=C3)C=CC=C4)=CS2)=O)=O
Biological Activity: Anticancer agent 36 (compound 11), a sulfonylurea derivative, is a potent antimicrobial and anticancer agent. Anticancer agent 36 inhibits the microbial growth of B. mycoides, E. coli, and C. albicans with a MIC between 0.156 and 0.039 mg/L. Anticancer agent 36 inhibits A549, PC3 cell growth with IC50s of 19.7 µg/mL, 11.9 µg/mL, respectively[1].
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Anticancer agent 36 | Anticancer agent 36 (compound 11), a sulfonylurea derivative, is a potent antimicrobial and anticancer agent. Anticancer agent 36 inhibits the microbial growth of B. mycoides, E. coli, and C. albicans with a MIC between 0.156 and 0.039 mg/L. Anticancer agent 36 inhibits A549, PC3 cell growth with IC50s of 19.7 µg/mL, 11.9 µg/mL, respectively. | |||||||||||||||||||||
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