290315-45-6
290315-45-6
Chemical Structure
BMS 299897
- CAS No.: 290315-45-6
- Formula:C24H21ClF3NO4S
- Molecular Weight:511.94
IUPAC Name: (R)-4-(2-(1-((4-chloro-N-(2,5-difluorophenyl)phenyl)sulfonamido)ethyl)-5-fluorophenyl)butanoic acid
InChIKey: IZAOBRWCUGOKNH-OAHLLOKOSA-N
SMILES: FC1=CC=C(F)C(N([C@@H](C2=C(CCCC(O)=O)C=C(F)C=C2)C)S(C3=CC=C(Cl)C=C3)(=O)=O)=C1
Biological Activity: BMS 299897 is a sulfonamide γ-secretase inhibitor with an IC50 of 7 nM for Aβ production inhibition in HEK293 cells stably overexpressing amyloid precursor protein (APP).
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BMS 299897 | 99.64% | BMS 299897 is a sulfonamide γ-secretase inhibitor with an IC50 of 7 nM for Aβ production inhibition in HEK293 cells stably overexpressing amyloid precursor protein (APP). | ||||||||||||||||||||
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Keywords
