2906132-49-6
Chemical Structure
CHIKV-IN-3
- CAS No.: 2906132-49-6
- Formula:C24H30ClNO
- Molecular Weight:383.95
IUPAC Name: 1-(4-((3-(guanidinomethyl)-4-methyl-6-oxopyridazin-1(6H)-yl)methyl)benzyl)guanidine dihydrochloride
InChIKey: IVEBPJVMVQQNHS-MWIKYDBZSA-N
SMILES: [H][C@@]12CCC([C@@H]([C@]1(CCCC2(C)C)C)C/C=C3C(NC4=C/3C=CC=C4Cl)=O)=C
Biological Activity: CHIKV-IN-3 is a potent against two low-passage CHIKV inhibitor with EC50 values of 1.55 and 0.14 μM for CHIKV-122508 and CHIKV-6708, respectively. CHIKV-IN-3 acts on the host cells to interfere with the viral replication. CHIKV-IN-3 displays minimal cytotoxic liability (CC50>100 μM). Prophylactic effect[1].
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CHIKV-IN-3 | CHIKV-IN-3 is a potent against two low-passage CHIKV inhibitor with EC50 values of 1.55 and 0.14 μM for CHIKV-122508 and CHIKV-6708, respectively. CHIKV-IN-3 acts on the host cells to interfere with the viral replication. CHIKV-IN-3 displays minimal cytotoxic liability (CC50>100 μM). Prophylactic effect. | |||||||||||||||||||||
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Keywords
