2916446-33-6
2916446-33-6
Chemical Structure
LK00764
- CAS No.: 2916446-33-6
- Formula:C16H15ClN4
- Molecular Weight:298.77
InChIKey: LVLXVQHHXDYEJB-UHFFFAOYSA-N
SMILES: ClC1=CC=C(C2=CC=C(C3=NN=C(CCN)N3)C=C2)C=C1
Biological Activity: LK00764 is a TAAR1 agonist with an EC50 of 4 nM. LK00764 alleviates Dizocilpine (HY-15084B)-induced hyperlocomotion, reduces vertical locomotor activity, attenuates spontaneous hyperlocomotion in dopamine transporter knockout rats, and inhibits stress-induced hyperthermia in rats. LK00764 can be used for the research of schizophrenia[1].
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LK00764 | LK00764 is a TAAR1 agonist with an EC50 of 4 nM. LK00764 alleviates Dizocilpine (HY-15084B)-induced hyperlocomotion, reduces vertical locomotor activity, attenuates spontaneous hyperlocomotion in dopamine transporter knockout rats, and inhibits stress-induced hyperthermia in rats. LK00764 can be used for the research of schizophrenia. | |||||||||||||||||||||
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References
Keywords
