2922110-00-5
2922110-00-5
Chemical Structure
Antitumor agent-135
- CAS No.: 2922110-00-5
- Formula:C68H77N13O16
- Molecular Weight:1332.42
InChIKey: XYUUYJGEFXHNSP-FZWUFXCXSA-N
SMILES: [H][C@@]12C3=C(C4=CC(OC(N(CCN(C(OCC5=C(N(C6=C5C(C(OC)=CC6=O)=O)CC(NCCOCCOCCOCCN7C=C(N=N7)C8=CC(NC9=NC=NC%10=CC(OCCOC)=C(C=C%109)OCCOC)=CC=C8)=O)C)=O)C)C)=O)=CC=C4N3)CCN1C(C%11=CC=CC=C%11N2C)=O
Biological Activity: Antitumor agent-135 (Compound 13) is a potent antitumor agent. Antitumor agent-135 induces cell apoptosis, with IC50s of 3.79 , 10.55, 1.14, and 4.14 μM for NSCLC cell lines (A549, H460, PC-9, and PC-9/GR)[1].
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Antitumor agent-135 | Antitumor agent-135 (Compound 13) is a potent antitumor agent. Antitumor agent-135 induces cell apoptosis, with IC50s of 3.79 , 10.55, 1.14, and 4.14 μM for NSCLC cell lines (A549, H460, PC-9, and PC-9/GR). | |||||||||||||||||||||
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