2. Apoptosis
  3. Apoptosis
  4. Antitumor agent-135

Antitumor agent-135 (Compound 13) is a potent antitumor agent. Antitumor agent-135 induces cell apoptosis, with IC50s of 3.79 , 10.55, 1.14, and 4.14 μM for NSCLC cell lines (A549, H460, PC-9, and PC-9/GR).

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Antitumor agent-135 Chemical Structure

Antitumor agent-135 Chemical Structure

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Antitumor agent-135 Related Antibodies

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Description

Antitumor agent-135 (Compound 13) is a potent antitumor agent. Antitumor agent-135 induces cell apoptosis, with IC50s of 3.79 , 10.55, 1.14, and 4.14 μM for NSCLC cell lines (A549, H460, PC-9, and PC-9/GR)[1].

Molecular Weight

1332.42

Formula

C68H77N13O16
SMILES

[H][C@@]12C3=C(C4=CC(OC(N(CCN(C(OCC5=C(N(C6=C5C(C(OC)=CC6=O)=O)CC(NCCOCCOCCOCCN7C=C(N=N7)C8=CC(NC9=NC=NC%10=CC(OCCOC)=C(C=C%109)OCCOC)=CC=C8)=O)C)=O)C)C)=O)=CC=C4N3)CCN1C(C%11=CC=CC=C%11N2C)=O
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Room temperature in continental US; may vary elsewhere.
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Antitumor agent-135 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antitumor agent-135Antitumor agent135Antitumor agent 135ApoptosisantitumorapoptosisA549H460PC-9PC-9/GRInhibitorinhibitorinhibit

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