2922808-66-8
2922808-66-8
Chemical Structure
Refinicopan
- CAS No.: 2922808-66-8
- Formula:C29H32N2O3
- Molecular Weight:456.58
IUPAC Name: 2-(2-((3'-(aminomethyl)-5-(6-azaspiro[2.5]octan-6-yl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)acetic acid
InChIKey: FIRMYSDKCGABGU-UHFFFAOYSA-N
SMILES: NCC1=CC=CC(C2=CC(N3CCC4(CC3)CC4)=CC(COC5=C(C=CC=C5)CC(O)=O)=C2)=C1
Biological Activity: Refinicopan is a complement factor D inhibitor with an IC50 of 10 nM. Refinicopan inhibits hemolysis of rabbit red blood cells. Refinicopan can be used to study diseases mediated by complement factor D[1].
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Refinicopan | Refinicopan is a complement factor D inhibitor with an IC50 of 10 nM. Refinicopan inhibits hemolysis of rabbit red blood cells. Refinicopan can be used to study diseases mediated by complement factor D. | |||||||||||||||||||||
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References
Keywords
