2923907-92-8
Chemical Structure
GLI1-IN-1
- CAS No.: 2923907-92-8
- Formula:C42H60N2O9
- Molecular Weight:736.93
InChIKey: CXELXEUAFXDMTL-SWIMQBEISA-N
SMILES: CN1CCN(CC(O[C@@H]2CC3=CC[C@]([C@](CC[C@@]4(O)[C@@H](OC([C@@H](C)CC)=O)C)(O)[C@]4(C)[C@H](OC(/C=C/C5=CC=CC=C5)=O)C6)(O)C6[C@@]3(C)CC2)=O)CC1
Biological Activity: GLI1-IN-1 (CBC-1) is a GLI-1 inhibitor with excellent water solubility and anticancer activity. GLI1-IN-1 can induce apoptosis and suppress the growth of colorectal cancer by inhibiting the Hedgehog(HH) (IC50=1.3 μM) pathway[1].
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GLI1-IN-1 | GLI1-IN-1 (CBC-1) is a GLI-1 inhibitor with excellent water solubility and anticancer activity. GLI1-IN-1 can induce apoptosis and suppress the growth of colorectal cancer by inhibiting the Hedgehog(HH) (IC50=1.3 μM) pathway. | |||||||||||||||||||||
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Keywords