2925078-55-1
Chemical Structure
CRBN ligand-378
- CAS No.: 2925078-55-1
- Formula:C13H10BrN3O2
- Molecular Weight:320.15
IUPAC Name: 1-(4-bromoisoquinolin-7-yl)dihydropyrimidine-2,4(1H,3H)-dione
InChIKey: AKVHPQRJCRHFOM-UHFFFAOYSA-N
SMILES: O=C1NC(=O)CCN1C=2C=CC=3C(Br)=CN=CC3C2
Biological Activity: CRBN ligand-378 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-378 can be linked to a target protein ligand via a linker to form a PROTAC.
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CRBN ligand-378 | CRBN ligand-378 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-378 can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords