2938997-23-8
Chemical Structure
MAK683-C2-acid hydrochloride
- CAS No.: 2938997-23-8
- Formula:C23H22ClFN6O3
- Molecular Weight:484.91
IUPAC Name: 3-(5-(5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)amino)-[1,2,4]triazolo[4,3-c]pyrimidin-8-yl)-6-methylpyridin-2-yl)propanoic acid hydrochloride
InChIKey: YHZAJYSDLJSRJW-UHFFFAOYSA-N
SMILES: FC1=CC=C2C(CCO2)=C1CNC3=NC=C(C4=C(C)N=C(CCC(O)=O)C=C4)C5=NN=CN35.Cl
Biological Activity: MAK683-CH2CH2COOH binds to EED (embryonic ectoderm development protein). MAK683-CH2CH2COOH and a VHL ligand for the E3 ubiquitin ligase have been used to design PROTAC EED degrader-1 (HY-130614) and PROTAC EED degrader-2 (HY-130615)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MAK683-C2-acid hydrochloride | 99.60% | MAK683-CH2CH2COOH binds to EED (embryonic ectoderm development protein). MAK683-CH2CH2COOH and a VHL ligand for the E3 ubiquitin ligase have been used to design PROTAC EED degrader-1 (HY-130614) and PROTAC EED degrader-2 (HY-130615). | ||||||||||||||||||||
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Keywords
