2953287-57-3
2953287-57-3
Chemical Structure
BET-IN-23
- CAS No.: 2953287-57-3
- Formula:C29H34FN3O5
- Molecular Weight:523.60
InChIKey: LOOFPBVYOVHBCL-UHFFFAOYSA-N
SMILES: CN1C=C(C(NCC(N2CCOCC2)=O)=CC1=O)C3=C(C=CC(C(C)(O)C)=C3)OC4=C(C=C(C=C4C)F)C
Biological Activity: Bet-in-23 (Compound 23) is a BD2-selective BET inhibitor with an IC50 of 2.9 nM. BET-IN-23 has anticancer activity and can significantly inhibit the proliferation of acute myeloid leukemia (AML) cell lines by inducing G0/G1 arrest and apoptosis in vitro[1].
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BET-IN-23 | Bet-in-23 (Compound 23) is a BD2-selective BET inhibitor with an IC50 of 2.9 nM. BET-IN-23 has anticancer activity and can significantly inhibit the proliferation of acute myeloid leukemia (AML) cell lines by inducing G0/G1 arrest and apoptosis in vitro. | |||||||||||||||||||||
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References
Keywords
