2954888-39-0
Chemical Structure
Mtb-IN-5
- CAS No.: 2954888-39-0
- Formula:C24H24N2O4S
- Molecular Weight:436.52
InChIKey: LHVKTOZEGWRTSX-UHFFFAOYSA-N
SMILES: O=C(C1CSC2=C(C3CC3)C(C4=CC(C5=CC=C(C(C)(C)C)C=C5)=NO4)=CC(N21)=O)O
Biological Activity: Mtb-IN-5 (compound (-)17j) is an isoxazole, with anti-Mycobacterium tuberculosis (Mtb) activity. Mtb-IN-4 inhibits Mtb respiration and biofilm formation in macrophage, and enhances antibiotic isoniazid (INH) inhibition against INH-resistant Mtb mutant[1].
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Mtb-IN-5 | Mtb-IN-5 (compound (-)17j) is an isoxazole, with anti-Mycobacterium tuberculosis (Mtb) activity. Mtb-IN-4 inhibits Mtb respiration and biofilm formation in macrophage, and enhances antibiotic isoniazid (INH) inhibition against INH-resistant Mtb mutant. | |||||||||||||||||||||
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Keywords