2957895-40-6
2957895-40-6
Chemical Structure
YAP/TEAD-IN-2
- CAS No.: 2957895-40-6
- Formula:C21H20N6O3
- Molecular Weight:404.42
InChIKey: KJSGGASKNWXJFA-UHFFFAOYSA-N
SMILES: O=C(C1=NN=C(C(C=NN23)=C3NC(C4=CC=C(C5CCCCC5)C=C4)=CC2=O)O1)N
Biological Activity: YAP/TEAD-IN-2 (Compound T-1) is a YAP/TEAD inhibitor. YAP/TEAD-IN-2 inhibits the luciferase activity driven by YAP/TEAD in 293T cells. YAP/TEAD-IN-2 exhibits strong anti-proliferative activity against human pleural mesothelioma NCI-H226 cells. YAP/TEAD-IN-2 can be used for the study of diseases associated with Hippo pathway dysregulation, particularly cancers[1].
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YAP/TEAD-IN-2 | 95.0% | YAP/TEAD-IN-2 (Compound T-1) is a YAP/TEAD inhibitor. YAP/TEAD-IN-2 inhibits the luciferase activity driven by YAP/TEAD in 293T cells. YAP/TEAD-IN-2 exhibits strong anti-proliferative activity against human pleural mesothelioma NCI-H226 cells. YAP/TEAD-IN-2 can be used for the study of diseases associated with Hippo pathway dysregulation, particularly cancers. | ||||||||||||||||||||
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