2959494-30-3
2959494-30-3
Chemical Structure
BPA-B9
- CAS No.: 2959494-30-3
- Formula:C25H26N4O2
- Molecular Weight:414.50
IUPAC Name: N-(2'-(4-(hydroxymethyl)piperidin-1-yl)-[4,4'-bipyridin]-2-yl)cinnamamide
InChIKey: KEIAPUMYBMYMQR-VOTSOKGWSA-N
SMILES: O=C(NC1=NC=CC(C2=CC(N3CCC(CC3)CO)=NC=C2)=C1)/C=C/C4=CC=CC=C4
Biological Activity: BPA-B9 is a RXRα ligand and antagonist targeting the pRXRα-PLK1 interaction. BPA-B9 has excellent RXRα-binding affinity (KD=39.29 ± 1.12 nM). BPA-B9 inhibits the proliferation of cancer cells by inducing mitotic arrest and cell apoptosis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BPA-B9 | 98.50% | BPA-B9 is a RXRα ligand and antagonist targeting the pRXRα-PLK1 interaction. BPA-B9 has excellent RXRα-binding affinity (KD=39.29 ± 1.12 nM). BPA-B9 inhibits the proliferation of cancer cells by inducing mitotic arrest and cell apoptosis. | ||||||||||||||||||||
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