2978517-43-8
2978517-43-8
Chemical Structure
DCLK1-IN-2
- CAS No.: 2978517-43-8
- Formula:C26H32N8O3S
- Molecular Weight:536.65
InChIKey: ILBZLLHFIMKVOD-UHFFFAOYSA-N
SMILES: CC(C)S(C1=C(NC2=NC(NC3=C(OC)C=C(N4CCN(C)CC4)C=C3)=NC5=C2N=CN5)C=CC=C1)(=O)=O
Biological Activity: DCLK1-IN-2 (compound I-5) is a potent DCLK1 inhibitor with an IC50 of 171.3 nM. DCLK1-IN-2 shows remarkable antiproliferative effects on SW1990 cell lines (IC50 of 0.6 μM) and in vivo antitumor potency[1].
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DCLK1-IN-2 | DCLK1-IN-2 (compound I-5) is a potent DCLK1 inhibitor with an IC50 of 171.3 nM. DCLK1-IN-2 shows remarkable antiproliferative effects on SW1990 cell lines (IC50 of 0.6 μM) and in vivo antitumor potency. | |||||||||||||||||||||
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