2982893-22-9
2982893-22-9
Chemical Structure
Tubulin polymerization-IN-48
- CAS No.: 2982893-22-9
- Formula:C20H15Cl2N3O
- Molecular Weight:384.26
InChIKey: LOQRRCBKTOIFLF-UHFFFAOYSA-N
SMILES: CC1=CC=C(C2=CN3C(C(C4=CC(Cl)=C(OC)C(Cl)=C4)=NC=C3)=N2)C=C1
Biological Activity: Tubulin polymerization-IN-48 (Compound 4k) is a tubulin polymerization inhibitor. Tubulin polymerization-IN-48 has a moderate effect on disruption of the microtubule network. Tubulin polymerization-IN-48 inhibits neuroblastoma cancer cell proliferation, with IC50s of 79 and 165 nM for Chp-134 and Kelly cell line[1].
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Tubulin polymerization-IN-48 | Tubulin polymerization-IN-48 (Compound 4k) is a tubulin polymerization inhibitor. Tubulin polymerization-IN-48 has a moderate effect on disruption of the microtubule network. Tubulin polymerization-IN-48 inhibits neuroblastoma cancer cell proliferation, with IC50s of 79 and 165 nM for Chp-134 and Kelly cell line. | |||||||||||||||||||||
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