2983892-65-3
Chemical Structure
Analgesic agent-2
- CAS No.: 2983892-65-3
- Formula:C21H21ClF2N4O2
- Molecular Weight:434.87
IUPAC Name: 5-chloro-2-(4,4-difluoroazepan-1-yl)-6-methyl-N-(3-oxoisoindolin-5-yl)nicotinamide
InChIKey: BIDXREXVLYVFET-UHFFFAOYSA-N
SMILES: CC1=C(C=C(C(N2CCCC(F)(CC2)F)=N1)C(NC3=CC4=C(CNC4=O)C=C3)=O)Cl
Biological Activity: Analgesic agent-2 is a selective and orally active NaV1.8 Channel inhibitor, with an IC50 of 50.18 nM in HEK293 cells stably expressing human NaV1.8 channel. Analgesic agent-2 has analgesic activity[1].
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Analgesic agent-2 | Analgesic agent-2 is a selective and orally active NaV1.8 Channel inhibitor, with an IC50 of 50.18 nM in HEK293 cells stably expressing human NaV1.8 channel. Analgesic agent-2 has analgesic activity. | |||||||||||||||||||||
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Keywords