2994215-72-2
2994215-72-2
Chemical Structure
Akt/NF-κB/MAPK-IN-1
- CAS No.: 2994215-72-2
- Formula:C38H56N2O4
- Molecular Weight:604.86
InChIKey: GTPJGHSNVSPXNR-WSFWIEFXSA-N
SMILES: O[C@@H]1[C@@]2([H])[C@@]3([H])[C@@]([C@@](CC3)([H])[C@H](C)CCC(N4CCN(CC4)C(/C=C/C5=CC=C(C=C5)C)=O)=O)(CC[C@]2([H])[C@@]6([C@](C[C@@H](CC6)O)([H])C1)C)C
Biological Activity: Akt/NF-κB/MAPK-IN-1 (compound 2m) is a potent and orally active inhibitor against NO (IC50=7.70 μM) with no significant toxicity. Akt/NF-κB/MAPK-IN-1 shows anti-inflammatory activity by inhibiting Akt/NF-κB and MAPK signaling pathways[1].
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Akt/NF-κB/MAPK-IN-1 | Akt/NF-κB/MAPK-IN-1 (compound 2m) is a potent and orally active inhibitor against NO (IC50=7.70 μM) with no significant toxicity. Akt/NF-κB/MAPK-IN-1 shows anti-inflammatory activity by inhibiting Akt/NF-κB and MAPK signaling pathways. | |||||||||||||||||||||
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