2999672-72-7
Chemical Structure
(R)-ZG197
- CAS No.: 2999672-72-7
- Formula:C28H35F3N4O3
- Molecular Weight:532.60
IUPAC Name: (6S,9aS)-6-((S)-sec-butyl)-8-((R)-1-(naphthalen-1-yl)ethyl)-4,7-dioxo-N-(4,4,4-trifluorobutyl)hexahydro-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide
InChIKey: BAZGDIOJCKGDHH-RHDWJPPYSA-N
SMILES: O=C(N1CCC(N([C@H]2[C@@H](C)CC)[C@]1([H])CN([C@H](C)C3=C(C=CC=C4)C4=CC=C3)C2=O)=O)NCCCC(F)(F)F
Biological Activity: (R)-ZG197 is a highly selective Staphylococcus aureus Caseinolytic protease P (SaClpP) activator with an EC50 of 1.5 μM. (R)-ZG197 also activates Homo sapiens ClpP (HsClpP) with an EC50 of 31.4 μM[1].
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(R)-ZG197 | (R)-ZG197 is a highly selective Staphylococcus aureus Caseinolytic protease P (SaClpP) activator with an EC50 of 1.5 μM. (R)-ZG197 also activates Homo sapiens ClpP (HsClpP) with an EC50 of 31.4 μM. | |||||||||||||||||||||
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Keywords
