3001295-81-1

PTP1B-IN-20 Chemical Structure
3001295-81-1

Chemical Structure

PTP1B-IN-20

  • CAS No.: 3001295-81-1
  • Formula:C26H28O15
  • Molecular Weight:580.49

IUPAC Name: 6'-chloro-[2,2'-bipyridin]-6-ol

InChIKey: FATNCJZCOOPLKZ-YJWXBJJPSA-N

SMILES: OC1=C(C2=C(C(C3=C(C2=O)C=C(C(C)=C3O)O[C@H]4[C@H](O)[C@H]([C@@H]([C@H](O4)CO[C@@H]5OC[C@@H](O)[C@H](O)[C@H]5O)O)O)=O)C=C1)O

Biological Activity: PTP1B-IN-20 is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B; IC50=1.05 μM) over the highly homologous T-cell protein tyrosine phosphatase (TCPTP; IC50=78.0 μM), which is a key target for type 2 diabetes inhibition[1].

Cat. No. Product Name Purity Description Pricing
HY-N10648 		PTP1B-IN-20 PTP1B-IN-20 is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B; IC50=1.05 μM) over the highly homologous T-cell protein tyrosine phosphatase (TCPTP; IC50=78.0 μM), which is a key target for type 2 diabetes inhibition.
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