3008988-49-3
3008988-49-3
Chemical Structure
10m/ZS44
- CAS No.: 3008988-49-3
- Formula:C31H32N2O6
- Molecular Weight:528.60
InChIKey: JVDABCHLQNLAEA-SDNWHVSQSA-N
SMILES: COC1=CC(C(/C=C/C2=CC=C(C=C2)C(N3CCN(C34COC4)CC5=CC=CC=C5)=O)=O)=CC(OC)=C1OC
Biological Activity: 10m/ZS44 is a blood-brain barrier-permeable Glioblastoma (GBM) inhibitor. 10m/ZS44 significantly inhibits GBM tumor growth in a mouse xenograft model. 10m/ZS44 also activates the SIRT1/p53-mediated apoptosis pathway, thereby inhibiting the proliferation of U251 cells[1].
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10m/ZS44 | 10m/ZS44 is a blood-brain barrier-permeable Glioblastoma (GBM) inhibitor. 10m/ZS44 significantly inhibits GBM tumor growth in a mouse xenograft model. 10m/ZS44 also activates the SIRT1/p53-mediated apoptosis pathway, thereby inhibiting the proliferation of U251 cells. | |||||||||||||||||||||
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References
Keywords
