3011029-58-3
Chemical Structure
XL01126
- CAS No.: 3011029-58-3
- Formula:C50H64ClFN10O6S2
- Molecular Weight:1019.69
IUPAC Name: 4-bromo-2-(dimethoxymethyl)pyridine
InChIKey: HKSBXNVKPFTBIG-SHFRUIRLSA-N
SMILES: O=C([C@H]1N(C([C@@H](NC(C2(F)CC2)=O)C(C)(SC[C@@H]3CC[C@@H](CN4CCN(C(C5=CC=C(NC6=NC=C(Cl)C(NC)=N6)C(OC)=C5)=O)CC4)CC3)C)=O)C[C@H](O)C1)NCC7=CC=C(C8=C(C)N=CS8)C=C7
Biological Activity: XL01126 is a potent LRRK2 PROTAC (DC50: 14 nM (G2019S LRRK2) and 32 nM (WT LRRK2)). XL01126 crosses the blood-brain barrier and is used as a degradation probe in Parkinson's disease research. XL01126 can be used to study the non-catalytic and framework functions of LRRK2[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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XL01126 | 98.90% | XL01126 is a potent LRRK2 PROTAC (DC50: 14 nM (G2019S LRRK2) and 32 nM (WT LRRK2)). XL01126 crosses the blood-brain barrier and is used as a degradation probe in Parkinson's disease research. XL01126 can be used to study the non-catalytic and framework functions of LRRK2. | ||||||||||||||||||||
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Keywords
