3017222-33-9
3017222-33-9
Chemical Structure
Ferroptosis-IN-3
- CAS No.: 3017222-33-9
- Formula:C15H11ClN2O2
- Molecular Weight:286.71
InChIKey: XHJJFKLFMMWFIR-UHFFFAOYSA-N
SMILES: OC1=C(C2=CC=C(O)C=C2)NN=C1C3=CC=C(Cl)C=C3
Biological Activity: Ferroptosis-IN-3 (Compound 25) is a ferroptosis inhibitor. Ferroptosis-IN-3 inhibits RSL3-induced ferroptosis (EC50: 8.6 nM in HT-1080 cells). Ferroptosis-IN-3 scavenges DPPH and ABTS radicals (EC50: 3.94 and 6.3 μM respectively). Ferroptosis-IN-3 decreases lipid peroxidation[1].
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Ferroptosis-IN-3 | Ferroptosis-IN-3 (Compound 25) is a ferroptosis inhibitor. Ferroptosis-IN-3 inhibits RSL3-induced ferroptosis (EC50: 8.6 nM in HT-1080 cells). Ferroptosis-IN-3 scavenges DPPH and ABTS radicals (EC50: 3.94 and 6.3 μM respectively). Ferroptosis-IN-3 decreases lipid peroxidation. | |||||||||||||||||||||
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