3018834-98-2
3018834-98-2
Chemical Structure
MAT2A-IN-20
- CAS No.: 3018834-98-2
- Formula:C26H24F2N6O4
- Molecular Weight:522.50
InChIKey: QSIIZWGBIZXFLM-UHFFFAOYSA-N
SMILES: O=C1C(C2=CC3=C(N=C(C(C)(C)O)N3C)C=C2)=NC4=C(N1C5=CC=C(C=C5)OC(F)F)N=C(OCC)N=C4
Biological Activity: MAT2A-IN-20 (Compound A49) is an inhibitor for methionine adenosyltransferase 2A (MAT2A) with an IC50 ≤50 nM. MAT2A-IN-20 inhibits human UGT1A1 with an IC50 of 28.45 μM. MAT2A-IN-20 exhibits antitumor in mouse models[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
MAT2A-IN-20 | MAT2A-IN-20 (Compound A49) is an inhibitor for methionine adenosyltransferase 2A (MAT2A) with an IC50 ≤50 nM. MAT2A-IN-20 inhibits human UGT1A1 with an IC50 of 28.45 μM. MAT2A-IN-20 exhibits antitumor in mouse models. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
