3024369-07-8
3024369-07-8
Chemical Structure
KY0418
- CAS No.: 3024369-07-8
- Formula:C28H35F3N8O3
- Molecular Weight:588.62
InChIKey: DBKLLNDNWVOXSC-ZIFCJYIRSA-N
SMILES: O=C(N1C2=CC=C(N3C[C@H](C)O[C@H](C)C3)N=C2)C4(CCCC4)C5=C1N=C(COC(N6[C@@H](C(F)(F)F)CCC6)=N)N=C5N
Biological Activity: KY0418 is a selective GPX4 inhibitor. KY0418 selectively and covalently modifies the selenocysteine residue of GPX4 and inhibits GPX4 activity. KY0418 induces ferroptosis and suppresses cell proliferation. KY0418 can be used for the study of ferroptosis and cancer[1].
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KY0418 | KY0418 is a selective GPX4 inhibitor. KY0418 selectively and covalently modifies the selenocysteine residue of GPX4 and inhibits GPX4 activity. KY0418 induces ferroptosis and suppresses cell proliferation. KY0418 can be used for the study of ferroptosis and cancer. | |||||||||||||||||||||
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References
Keywords
