3026084-13-6
3026084-13-6
Chemical Structure
(R,S,R)-TRPV4 antagonist 5
- CAS No.: 3026084-13-6
- Formula:C25H27FN6O3
- Molecular Weight:478.52
InChIKey: GMWREKJBHSGOTM-QTLGCAHFSA-N
SMILES: C[C@@]1(C[C@]2(CC[C@@H]1F)CN(C3=NC=C(C(C)(O)C)N=C3)C(O2)=O)CN4C5=CC(C#N)=CC=C5N=C4
Biological Activity: (R,S,R)-TRPV4 antagonist 5 (example 5B) is a TRPV4 antagonist. (R,S,R)-TRPV4 antagonist 5 inhibits calcium influx by antagonizing TRPV4 channels, thereby blocking cellular responses triggered by mechanical stress, heat, or chemical stimuli[1].
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(R,S,R)-TRPV4 antagonist 5 | (R,S,R)-TRPV4 antagonist 5 (example 5B) is a TRPV4 antagonist. (R,S,R)-TRPV4 antagonist 5 inhibits calcium influx by antagonizing TRPV4 channels, thereby blocking cellular responses triggered by mechanical stress, heat, or chemical stimuli. | |||||||||||||||||||||
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