3027834-94-9
3027834-94-9
Chemical Structure
tert-Butyl (trans-4-((4-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)piperazin-1-yl)methyl)cyclohexyl)carbamate
- CAS No.: 3027834-94-9
- Formula:C29H39N5O6
- Molecular Weight:553.66
IUPAC Name: tert-butyl ((1r,4r)-4-((4-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)piperazin-1-yl)methyl)cyclohexyl)carbamate
InChIKey: HSYCLKKVRDTPFG-CIQKOQMRSA-N
SMILES: O=C1N(C(=O)C=2C1=CC(=CC2)N3CCN(C[C@@H]4CC[C@@H](NC(OC(C)(C)C)=O)CC4)CC3)C5C(=O)NC(=O)CC5
Biological Activity: tert-Butyl (trans-4-((4-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)piperazin-1-yl)methyl)cyclohexyl)carbamate is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
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tert-Butyl (trans-4-((4-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)piperazin-1-yl)methyl)cyclohexyl)carbamate | tert-Butyl (trans-4-((4-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)piperazin-1-yl)methyl)cyclohexyl)carbamate is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC. | |||||||||||||||||||||
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