3031515-48-4
3031515-48-4
Chemical Structure
ROCK2-IN-5
- CAS. Nr.: 3031515-48-4
- Formula:C23H25N3O5S
- Molecular Weight:455.53
IUPAC Name: 3-(3,4-dihydroxyphenyl)-1-(4-(isoquinolin-5-ylsulfonyl)-1,4-diazepan-1-yl)propan-1-one
InChIKey: YJSJKVMKZYLGQP-UHFFFAOYSA-N
SMILES: O=C(CCC1=CC(O)=C(C=C1)O)N2CCCN(S(C3=C4C(C=NC=C4)=CC=C3)(=O)=O)CC2
Biological Activity: ROCK2-IN-5 (compound 1d) is a hybrid compound containing structural fragments of the Rho kinase inhibitor fasudil and the NRF2 inducers caffeic and ferulic acids. ROCK2-IN-5 has good multitarget profile and good tolerability. ROCK2-IN-5 has the potential for thr research of Amyotrophic lateral sclerosis (ALS) with a SOD1 mutation[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
ROCK2-IN-5 | ROCK2-IN-5 (compound 1d) is a hybrid compound containing structural fragments of the Rho kinase inhibitor fasudil and the NRF2 inducers caffeic and ferulic acids. ROCK2-IN-5 has good multitarget profile and good tolerability. ROCK2-IN-5 has the potential for thr research of Amyotrophic lateral sclerosis (ALS) with a SOD1 mutation. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
