3032733-05-1
3032733-05-1
Chemical Structure
LRRK2-IN-12
- CAS 番号: 3032733-05-1
- Formula:C18H17ClN8O2
- Molecular Weight:412.83
InChIKey: LDFXRLNXLQBRHK-UHFFFAOYSA-N
SMILES: CC1=C(NC2=NC3=C4C=N2)C(OCCCN3N=C4Cl)=NN1C5=CC=CN=C5OC
Biological Activity: LRRK2-IN-12 (compound 1) inhibits the activity of LRRK2 G20195 (IC50=0.45 nM), LRRK2 WT (IC50=1.1 nM) and LRRK2 WT ADP-Glo (IC50=0.46 nM). LRRK2-IN-12 can be used for Alzheimer's Disease research[1].
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LRRK2-IN-12 | LRRK2-IN-12 (compound 1) inhibits the activity of LRRK2 G20195 (IC50=0.45 nM), LRRK2 WT (IC50=1.1 nM) and LRRK2 WT ADP-Glo (IC50=0.46 nM). LRRK2-IN-12 can be used for Alzheimer's Disease research. | |||||||||||||||||||||
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