3034052-35-9
Chemical Structure
KRASG12D-IN-4
- CAS No.: 3034052-35-9
- Formula:C35H31F3N6O2
- Molecular Weight:624.65
InChIKey: RFESPHBPXZKJSG-UTJMDAJZSA-N
SMILES: CC#CC1=C2C(N3CC4CC(N4)C3)=NC(OC[C@@]56CCCN5C[C@@H](C6)F)=NC2=C(C(C7=CC(O)=CC8=C7C(C#C)=C(C=C8)F)=N1)F
Biological Activity: KRASG12D-IN-4 (example 38) is a KRasG12D inhibitor with an IC50 of 3.3 nM. KRASG12D-IN-4 inhibits proliferation of pancreatic cancer ASPC-1 cells with an IC50 of 12 nM[1].
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KRASG12D-IN-4 | KRASG12D-IN-4 (example 38) is a KRasG12D inhibitor with an IC50 of 3.3 nM. KRASG12D-IN-4 inhibits proliferation of pancreatic cancer ASPC-1 cells with an IC50 of 12 nM. | |||||||||||||||||||||
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Keywords