3034215-86-3
3034215-86-3
Chemical Structure
CDD-1115
- CAS No.: 3034215-86-3
- Formula:C32H30N6O3
- Molecular Weight:546.62
SMILES: NC(C1=CC=CC(CNC(C2=CC=C3N=C(C4=CC5=C(C=NC=C5)C=C4)N([C@H]6C[C@@H](CC6)C(NC)=O)C3=C2)=O)=C1)=O
Biological Activity: CDD-1115 is a potent, selective inhibitor of BMPR2 with IC50 of 1.8 nM, Kiapp of 6.2 nM. CDD-1115 inhibits bone morphogenetic protein (BMP)-mediated gene expression. BMP controls cellular processes across many tissue types, including the kidney, skeletal muscle, heart, and reproductive organs. BMP induces ectopic bone formation[1].
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CDD-1115 | CDD-1115 is a potent, selective inhibitor of BMPR2 with IC50 of 1.8 nM, Kiapp of 6.2 nM. CDD-1115 inhibits bone morphogenetic protein (BMP)-mediated gene expression. BMP controls cellular processes across many tissue types, including the kidney, skeletal muscle, heart, and reproductive organs. BMP induces ectopic bone formation. | |||||||||||||||||||||
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References
Keywords
