3034663-23-2
3034663-23-2
Chemical Structure
Picoberin
- CAS No.: 3034663-23-2
- Formula:C17H13BrClNO
- Molecular Weight:362.65
IUPAC Name: (S)-10-bromo-11-chloro-5,6,13,13a-tetrahydro-8H-isoquinolino[3,2-a]isoquinolin-8-one
InChIKey: KMFMHNWLVDMGHT-INIZCTEOSA-N
SMILES: O=C1N2[C@@H](CC3=CC(Cl)=C(C=C31)Br)C4=C(CC2)C=CC=C4
Biological Activity: Picoberin is a low picomolar inhibitor of Hedgehog-induced osteoblast differentiation. Picoberin is a potent aryl hydrocarbon receptor (AhR) agonist. Picoberin inhibits Wnt3A-induced osteoblast differentiation of C3H10T1/2 cells. Picoberin can upregulate genes encoding phase I and II metabolic enzymes[1].
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Picoberin | Picoberin is a low picomolar inhibitor of Hedgehog-induced osteoblast differentiation. Picoberin is a potent aryl hydrocarbon receptor (AhR) agonist. Picoberin inhibits Wnt3A-induced osteoblast differentiation of C3H10T1/2 cells. Picoberin can upregulate genes encoding phase I and II metabolic enzymes. | |||||||||||||||||||||
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