3034700-27-8
3034700-27-8
Chemical Structure
Antitubercular agent-16
- CAS No.: 3034700-27-8
- Formula:C21H27N3S
- Molecular Weight:353.52
IUPAC Name: N-acetyl-D-glutamic-2,3,3,4,4-d5 acid
InChIKey: HBMBTLBDFPBSDK-UHFFFAOYSA-N
SMILES: CC1=CC(CNCC2CCCCC2)=C(N1C3=NC4=C(S3)C=CC=C4)C
Biological Activity: Antitubercular agent-16 (Compound 5q) is an antitubercular agent with MIC90 values of 0.40, 20.11, 23.51, 19.62, 10.93 and 13.62 μg/mL against M. tuberculosis H37Rv, CF16, CF61, CF76, CF152 and CF161, respectively. Antitubercular agent-16 shows low cytotoxicity against macrophages and pulmonary fibroblasts[1].
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Antitubercular agent-16 | Antitubercular agent-16 (Compound 5q) is an antitubercular agent with MIC90 values of 0.40, 20.11, 23.51, 19.62, 10.93 and 13.62 μg/mL against M. tuberculosis H37Rv, CF16, CF61, CF76, CF152 and CF161, respectively. Antitubercular agent-16 shows low cytotoxicity against macrophages and pulmonary fibroblasts. | |||||||||||||||||||||
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