3035124-25-2
Chemical Structure
Nrf2-ARE/hMAO-B/QR2 modulator 1
- CAS No.: 3035124-25-2
- Formula:C14H12N2O3
- Molecular Weight:256.26
IUPAC Name: (E)-5-(4-methoxystyryl)-3-(prop-2-yn-1-yl)-1,3,4-oxadiazol-2(3H)-one
InChIKey: SFKGQKWKUGEJCM-RMKNXTFCSA-N
SMILES: O=C1OC(/C=C/C2=CC=C(OC)C=C2)=NN1CC#C
Biological Activity: Nrf2-ARE/hMAO-B/QR2 modulator 1 is a Resveratrol-based multitarget-directed ligands with IC50s of 8.05, 9.83 and 0.57 μM for hMAO-B, NRF2 and QR2. Nrf2-ARE/hMAO-B/QR2 modulator 1 has neuroprotection, decreasing ROS production in okadaic acid-treated mice hippocampal slices[1]. Nrf2-ARE/hMAO-B/QR2 modulator 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Nrf2-ARE/hMAO-B/QR2 modulator 1 | 98.42% | Nrf2-ARE/hMAO-B/QR2 modulator 1 is a Resveratrol-based multitarget-directed ligands with IC50s of 8.05, 9.83 and 0.57 μM for hMAO-B, NRF2 and QR2. Nrf2-ARE/hMAO-B/QR2 modulator 1 has neuroprotection, decreasing ROS production in okadaic acid-treated mice hippocampal slices. Nrf2-ARE/hMAO-B/QR2 modulator 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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Keywords
