3036637-30-3
3036637-30-3
Chemical Structure
MTX-241F
- CAS No.: 3036637-30-3
- Formula:C20H14ClFN6
- Molecular Weight:392.82
InChIKey: OTZBLQVBEFIDEG-UHFFFAOYSA-N
SMILES: NC1=NC=C(C2=CC=C(N=CN=C3N4C5=CC(Cl)=C(F)C=C5CC4)C3=C2)C=N1
Biological Activity: MTX-241F is a selective small molecule inhibitor targeting EGFR and PI3 kinase family members. MTX-241F is able to penetrate the blood-brain barrier and control tumor growth over the long term. MTX-241F exhibits radiosensitizing activity in patient-derived DIPG neurospheres and may be used in the study of diffuse intrinsic pontine glioma (DIPG)[1].
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MTX-241F | MTX-241F is a selective small molecule inhibitor targeting EGFR and PI3 kinase family members. MTX-241F is able to penetrate the blood-brain barrier and control tumor growth over the long term. MTX-241F exhibits radiosensitizing activity in patient-derived DIPG neurospheres and may be used in the study of diffuse intrinsic pontine glioma (DIPG). | |||||||||||||||||||||
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References
Keywords
