3036933-32-8
Chemical Structure
Antitumor agent-58
- CAS No.: 3036933-32-8
- Formula:C27H28F3N9S
- Molecular Weight:567.63
IUPAC Name: 7-amino-3-(2-((2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)ethoxy)ethyl)amino)-2-oxoethyl)-1-ethyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carboxamide
InChIKey: JFKJKTUDSPBULG-IERDGZPVSA-N
SMILES: CC1=NC2=NC(SCC3=CC=C(C=C3)C(F)(F)F)=NN2C(N4CC[C@H]([C@H](C4)N(C5=NC=NC6=C5C=CN6)C)C)=C1
Biological Activity: Antitumor agent-58 (Compound C18) is an anti-tumor agent. Antitumor agent-58 effectively inhibits colony formation and cell migration of MGC-803 cells. Antitumor agent-58 induces apoptosis of MGC-803 cells through activation of the p38 and JNK signaling pathways. Antitumor agent-58 induces mitochondrial dysfunction of MGC-803 cells. Antitumor agent-58 effectively inhibits tumor growth of xenograft model bearing MGC-803 cells[1].
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Antitumor agent-58 | Antitumor agent-58 (Compound C18) is an anti-tumor agent. Antitumor agent-58 effectively inhibits colony formation and cell migration of MGC-803 cells. Antitumor agent-58 induces apoptosis of MGC-803 cells through activation of the p38 and JNK signaling pathways. Antitumor agent-58 induces mitochondrial dysfunction of MGC-803 cells. Antitumor agent-58 effectively inhibits tumor growth of xenograft model bearing MGC-803 cells. | |||||||||||||||||||||
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