3038638-82-0
3038638-82-0
Chemical Structure
CDK2-IN-52
- CAS No.: 3038638-82-0
- Formula:C38H47ClN10O4S
- Molecular Weight:775.36
InChIKey: FOIGMYJYKYHTAZ-UHFFFAOYSA-N
SMILES: O=C1NC(CCN1C2=NN(C)C3=C2C=CC(C4CCN(CC5CCN(CC5)C6=CC=CC(S(=O)(N7CCC(CC7)NC8=NC=C(C=N8)Cl)=O)=C6)CC4)=C3)=O
Biological Activity: CDK2-IN-52 (Compound Cpb No 39) is a selective cyclin-dependent kinase 2 (CDK2) inhibitor with a DC50 value of 1-10 nM. CDK2-IN-52 induces cell cycle arrest and suppresses tumor cell proliferation. CDK2-IN-52 is promising for research of CDK2-overexpressing malignancies such as breast and ovarian cancers[1].
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CDK2-IN-52 | CDK2-IN-52 (Compound Cpb No 39) is a selective cyclin-dependent kinase 2 (CDK2) inhibitor with a DC50 value of 1-10 nM. CDK2-IN-52 induces cell cycle arrest and suppresses tumor cell proliferation. CDK2-IN-52 is promising for research of CDK2-overexpressing malignancies such as breast and ovarian cancers. | |||||||||||||||||||||
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References
Keywords
