3038701-72-0
Chemical Structure
SARS-CoV-2 Mpro-IN-50
- No. CAS: 3038701-72-0
- Formula:C25H25F5N6O3
- Molecular Weight:552.50
InChIKey: DSQOUYWQSZADHG-NLWGTHIKSA-N
SMILES: FC1=CC([C@H]2[C@H](NC([C@H](NC(C(F)(F)F)=O)C(C)C)=O)CN(C(C3=NC=CN4C3=CN=C4)=O)CC2)=CC(F)=C1
Biological Activity: SARS-CoV-2 Mpro-IN-50 (Compound 30) is a noncovalent SARS-CoV-2 Mpro inhibitor with an IC50 of 14 nM. SARS-CoV-2 Mpro-IN-50 is also a pan-CoV Mpro inhibitor with IC50 s of 20-190 nM for SARS-CoV-1 Mpro, 229E Mpro, HKU1 Mpro, MERS Mpro, NL63 Mpro and OC43 Mpro. SARS-CoV-2 Mpro-IN-50 has significant antiviral activity against the SARS-CoV-2 omicron variant (EC50 : 22 nM). SARS-CoV-2 Mpro-IN-50 can be used for coronavirus infections research[1].
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SARS-CoV-2 Mpro-IN-50 | SARS-CoV-2 Mpro-IN-50 (Compound 30) is a noncovalent SARS-CoV-2 Mpro inhibitor with an IC50 of 14 nM. SARS-CoV-2 Mpro-IN-50 is also a pan-CoV Mpro inhibitor with IC50 s of 20-190 nM for SARS-CoV-1 Mpro, 229E Mpro, HKU1 Mpro, MERS Mpro, NL63 Mpro and OC43 Mpro. SARS-CoV-2 Mpro-IN-50 has significant antiviral activity against the SARS-CoV-2 omicron variant (EC50 : 22 nM). SARS-CoV-2 Mpro-IN-50 can be used for coronavirus infections research. | |||||||||||||||||||||
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Keywords
