3040106-93-9
3040106-93-9
Chemical Structure
IIP0943
- CAS No.: 3040106-93-9
- Formula:C26H28N6O3S
- Molecular Weight:504.60
InChIKey: YIEWJFWMQNWMJG-UHFFFAOYSA-N
SMILES: CN1CCN(C2=CC(NC3=NC=C(C)C(OC4=CC=CC5=C4SC(C(N)=O)=C5)=N3)=C(OC)C=C2)CC1
Biological Activity: IIP0943 is a selective inhibitor of PLK1 (polo-like kinase 1), with an IC50 of 5.1 nM for PLK1. In addition, IIP0943 exhibits antiproliferative activity against HCT116 cells, with an IC50 of 0.22 µM. These results suggest that IIP0943 holds promise for research in the field of cancer therapeutics[1].
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IIP0943 | IIP0943 is a selective inhibitor of PLK1 (polo-like kinase 1), with an IC50 of 5.1 nM for PLK1. In addition, IIP0943 exhibits antiproliferative activity against HCT116 cells, with an IC50 of 0.22 µM. These results suggest that IIP0943 holds promise for research in the field of cancer therapeutics. | |||||||||||||||||||||
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References
Keywords
