3043952-13-9
3043952-13-9
Chemical Structure
NLRP3-IN-72
- CAS No.: 3043952-13-9
- Formula:C19H20FN5O
- Molecular Weight:353.39
SMILES: CN1C2=CC=C(F)C=C2N=C1NC3=NC(C=C(CN(C)CC)C=C4)=C4O3
Biological Activity: NLRP3-IN-72 (Compound 2) is a benzimidazole derivative. NLRP3-IN-72 exhibits anti-inflammatory and antioxidant activities. NLRP3-IN-72 has an IC50 of 0.3 μM for NLRP3 IL-1β, a PD50 of 0.4 μM for protecting against pyroptosis, and an EC50 of 0.6 μM for inducing HO-1[1].
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NLRP3-IN-72 | NLRP3-IN-72 (Compound 2) is a benzimidazole derivative. NLRP3-IN-72 exhibits anti-inflammatory and antioxidant activities. NLRP3-IN-72 has an IC50 of 0.3 μM for NLRP3 IL-1β, a PD50 of 0.4 μM for protecting against pyroptosis, and an EC50 of 0.6 μM for inducing HO-1. | |||||||||||||||||||||
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References
Keywords
